Rule-of-5 / beyond-Ro5 flags

ro5_violations · Structure-derived (rule-based)

Count of Lipinski Ro5 violations (MW≤500, cLogP≤5, HBD≤5, HBA≤10). bRo5 oral-space classification (Doak 2014) carried in payload. Developability framing for macrocyclic peptides.

Computed value — a deterministic descriptor validated against independent reference implementations; not an experimental measurement, and it carries no evidence support-class. Computed from the chemical structure (RDKit) for peptide-scale molecules (MW ≤ 10 kDa). Not available for peptidoforms without a resolved structure (SMILES) — e.g. many disulfide-rich peptides.

• Peptides
  14,327
• Min
  0