Serum/plasma stability evidence

Measured entity

Measured material

Specific molecular form

Endpoint

ADMET domain

Metabolic & Proteolytic Stability

Value

Observation

Degraded quickly with half-lives of less than 0.5 h and are completely gone after 2 h.

Evidence role

Reported: reviewed reported observation that should not be pooled as a comparable value yet

Assay / model

stability

Condition

Not specified

Scientific source

DOI: 10.1371/journal.pone.0012684

Source: DRAMP

Developability