Protease stability evidence

Peptide

Measured material

Specific molecular form

Endpoint

ADMET domain

Metabolic & Proteolytic Stability

Value

Observation

All bioconjugates showed high stability in the presence of pepsin even after 27 h of incubation, as no proteolytic fragmentswere identified by LC-MS

Evidence role

Reported: reviewed reported observation that should not be pooled as a comparable value yet

Assay / model

stability

Condition

Not specified

Scientific source

DOI: 10.1021/bc100547p

Source: DRAMP

Developability