Blood-brain barrier (BBB) evidence

Peptide

Measured material

Peptide backbone

Endpoint

ADMET domain

Distribution / Barrier

Value

3.1 x 10^-7 cm/s

Measurement type

Permeability coefficient (Papp/Pe) — Apparent / endothelial permeability coefficient (cm/s) from an in vitro BBB monolayer or PAMPA assay.

Evidence role

Comparable: structured measurement intended for within-endpoint comparison when assay context matches

Assay / model

(Co)-culture · blood-brain barrier

Condition

Papp

Scientific source

DOI: 10.1016/j.ejps.2021.106054

Source: Brainpeps

Developability