Clearance evidence

Peptide

ATLPC0025642

Measured material

Peptide backbone

Endpoint

Clearance

ADMET domain

Excretion / Persistence

Value

Observation

In an elderly population, dose adjustments may be necessary due to a significant increase in the half-life (46%) and a significant decrease in the clearance (26%) of the drug.

Evidence role

Reported: reviewed reported observation that should not be pooled as a comparable value yet

Assay / model

human

Condition

Octreotide · 4e2c9856-1836-49f0-9472-4dbeeb408f39 · 12.3 Pharmacokinetics · clearance elderly relative decrease text · In an elderly population, dose adjustments may be necessary...

Scientific source

DailyMed

Open source

Clearance evidence

Developability

Resources

Measurement