Clearance evidence

Peptide

ATLPC0025642

Measured material

Peptide backbone

Endpoint

Clearance

ADMET domain

Excretion / Persistence

Value

Observation

Clearance was reduced by about 66% suggesting nonlinear kinetics of the drug at daily doses of 600 mcg/day compared to 150 mcg/day.

Evidence role

Reported: reviewed reported observation that should not be pooled as a comparable value yet

Assay / model

human

Condition

Octreotide · d0b7fe9e-7000-4b79-ba3b-291ce92c14f9 · 12.3 Pharmacokinetics · clearance relative reduction text · Clearance was reduced by about 66% suggesting nonlinear kinetics of...

Scientific source

DailyMed

Open source

Clearance evidence

Developability

Resources

Measurement