Bioavailability evidence
ATLXM0054578
A single reference-linked measurement — its measured value, assay/model context, and interpretation layer kept separate.
ATLXM0054578
A single reference-linked measurement — its measured value, assay/model context, and interpretation layer kept separate.
ATLXM0054578
The absolute bioavailability of cyclosporine administered as cyclosporine oral solution, USP MODIFIED has not been determined in adults. In studies of renal transplant, rheumatoid arthritis and psoriasis patients, the mean cyclosporine AUC was approximately 20% to 50% greater and the peak blood cyclosporine concentration (C max ) was approximately 40% to 106% greater following administration of cyclosporine oral solution, USP MODIFIED compared to following administration of Sandimmune (cyclosporine oral solution, USP).
This page treats the row as evidence attached to an endpoint and assay context. The layer describes how the row can be interpreted; it is not a safety or developability score by itself.