Evidence·Excretion / Persistence
ReportedClearance evidence
ATLXM0054624
A single reference-linked measurement — its measured value, assay/model context, and interpretation layer kept separate.
Stack
ATLXM0054624
A single reference-linked measurement — its measured value, assay/model context, and interpretation layer kept separate.
ATLXM0054624
In a study performed in 4 subjects with end-stage renal disease (creatinine clearance < 5 mL/min), an intravenous infusion of 3.5 mg/kg of cyclosporine over 4 hours administered at the end of a hemodialysis session resulted in a mean volume of distribution (Vdss) of 3.49 L/kg and systemic clearance (CL) of 0.369 L/hr/kg.
This page treats the row as evidence attached to an endpoint and assay context. The layer describes how the row can be interpreted; it is not a safety or developability score by itself.
