Peptide·map backed

ATLPC0012633

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Length
2 aa
Monoisotopic mass
330.2 Da
Net charge @ pH 7.4
2.00
Isoelectric point
12.50
GRAVY
-4.500

Coveragecounts only · not riskATLPC0012633

Measurements
0
Endpoints
0
Domains
0/5
Products
—

No matrix stability evidence
No clearance evidence
No immunogenicity context
No sequence liability cues

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Open the matching evidence section below

All evidence index

Exposure / Absorption

No evidence

Distribution / Barrier

No evidence

Metabolic & Proteolytic Stability

No evidence

Excretion / Persistence

No evidence

Toxicity / Safety

No evidence

Sequence & molecular identity

1 forms

Reviewed sequence, peptidoform forms, chemical representation, 3D references, and covalent topology used to interpret this peptide identity.

Sequence & peptidoform

Identity summarySpecific molecular form represented

Identity status: Specific molecular form represented
Residues: 2
Peptidoform features: 0
Documented molecular forms: 1
Representations: 4

Documented molecular forms1 form linked to this peptide identity

Form	Topology	Modifications	Connections	Representations	Measurements
ATLPF0013829	—	2	—	1	—

Residue view

Residue display

2 residues

R1R2

Secondary structureα-helix (H)β-strand (E)coil (C)

Side-chain classNonpolarPolarBasic (+)Acidic (−)Modified

Soft tints mark standard side-chain classes for scanning. Primary emphasis is reserved for reported modifications, termini, secondary-structure tracks, and topology links.

Peptidoform features

Features are shown only when a reported notation or topology record supports them.

No terminal modification, residue-level marker, disulfide, staple, coordination, or other topology signal is currently available.

Structure & chemistry

Chemical representationSMILES available

2D structure·RDKit.js

rendering molecule…

Canonical SMILES

N=C(N)NCCC[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)O

Representation class

How the current release can interpret this identity chemically.

map backed

Parent-residue sequence

Residue string used for positional interpretation when available.

RR

HELM

Polymer notation for modified peptide representation when available.

{conj:C14 = tetradecanoic acid}RR{ct:Amid}

SMILES

Chemical graph string used for atom-level 2D depiction when available.

N=C(N)NCCC[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)O

3D structure references1 reference

3D coordinates·PEPstrMOD predictionpredicted

PEPstrMOD prediction·reference selected·length 2 aa·confidence predicted

Link	Method	Confidence	Match
Open	PEPstrMOD model	predicted	2 aa

Covalent topology & modifications1 signal

Feature	Positions	Interpretation	Link
Form-level topology	ATLPF0013829	Open-chain form. Residue-level connection endpoints are shown separately when available.	Not linked

Physicochemical profile

10 descriptors

Computed sequence-derived descriptors and any measured physicochemical evidence such as lipophilicity. Computed values are interpretation aids, not experimental ADMET measurements.

Core descriptors2 aa · pI 12.5 · GRAVY -4.50

Length: 2 aa
Monoisotopic mass: 330.21 Da
Average mass: 330.39 Da
Net charge at pH 7.4: 2.00
Estimated pI: 12.50
GRAVY: -4.500
KD-positive residues: 0.0%
Aromatic residues: 0.0%

Developability interpretation

Ionization context: pH 7.4 separated from pI
Hydrophobicity balance: Leans hydrophilic
Amphipathic moment (μH): 2.89
Computation boundary: Standard-sequence only

Charge & residue composition

pH charge context

Modeled net charge across common formulation and assay pH checkpoints.

pH 2

2.98

pH 5

2.04

pH 6

2.00

pH 7.4

1.94

pH 9

1.28

pH 12

0.52

Residue-class composition

Grouped composition is often more interpretable than a long amino-acid list.

Basic (K,R,H)

2 · 100.0%

Top residues

R2100.0%

Hydropathy & amphipathic windows

Hydropathy windows

Seven-residue sliding windows expose local patches hidden by whole-sequence GRAVY.

Most hydrophobic window

1-2

GRAVY -4.500

Most hydrophilic window

1-2

GRAVY -4.500

1 local hydropathy window scanned. A local patch is context for solubility, adsorption, and membrane interaction review, not a standalone endpoint.

Amphipathic-window scan

Top alpha-helix hydrophobic-moment windows across 12, 15, 18, and 21 residues.

Sequence is shorter than the local amphipathic-window sizes used here.

Sequence-liability cues

Sequence-liability notes

Motifs are review prompts for formulation or CMC interpretation; they are not degradation predictions.

No conservative sequence-liability motifs from the current rule set are present.

Method notes

Charge model: side-chain pKa D 3.9, E 4.1, C 8.5, Y 10.1, H 6.5, K 10.8, R 12.5 with EMBOSS termini. pI is estimated by binary search on modeled net charge. Hydropathy uses Kyte-Doolittle values; hydrophobic moment follows the Eisenberg alpha-helix vector-sum convention. When the basis is a parent-residue sequence, modified chemistry is intentionally not inferred.

Computed developability descriptors

Deterministic descriptors computed from the reviewed sequence or chemical structure (RDKit), each anchored to a literature method. These are computed estimates for developability interpretation — not experimental measurements — and are validated against independent reference implementations.

Sequence-derived

Computed from the standard parent-residue sequence; protein-origin metrics defined at any length.

Aliphatic index

0.00

Instability index

291.4

Above 40 — predicted unstable in vitro.

Boman index

14.92 kcal/mol

Above 2.48 — elevated potential protein-binding.

Molar extinction coefficient (280 nm)

0 M⁻¹·cm⁻¹

A280 (1 g/L) ≈ 0.00

Structure-derived (developability)

Computed from the representative peptidoform's chemical structure. Rule-of-5 / beyond-Ro5 framing per Lipinski/Doak.

Topological polar surface area

216.2 Å²

Computed logP (Crippen)

-2.59

Computed logP — distinct from the measured logD endpoint.

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Rule-of-5 / beyond-Ro5 flags

Beyond bRo5

1 Ro5 violation · MW 330.39 Da

Data access & reproducibility

Stable record access, analysis-ready files, and scripted retrieval for reproducing this profile view.

Record scopePublic release

ATL peptide ID: ATLPC0012633
Identity type: canonical sequence
ADMET endpoints: 0
Evidence records: 0
Reference groups: 1
Release view: Public release

Data access

Structured peptide profile

JSON

Peptide-specific profile used by this page, including identity and evidence context.

Open JSON

Peptide catalogue

TSV

Complete frozen peptide table. Filter the ATL peptide ID column locally to isolate this record.

Download catalogue

Measurement catalogue

TSV

Complete frozen measurement table. Join or filter by ATL peptide ID for peptide-level analysis.

Download measurements

Programmatic access

The request returns the same structured peptide record used by this profile. The tabular downloads are complete frozen release tables and should be filtered locally by ATL peptide ID.

Open endpoint

GET /api/v1/peptides/ATLPC0012633

open

curl -sS 'https://admetatlas.scbdd.com/api/v1/peptides/ATLPC0012633' \
  -H 'accept: application/json' \
  -H 'X-Visibility: public_release'

Form

Topology

Modifications

Connections

Representations

Measurements

ATLPF0013829

—

Link

Method

Confidence

Match

Open

PEPstrMOD model

predicted

2 aa

Feature

Positions

Interpretation

Link

Form-level topology

ATLPF0013829

Open-chain form. Residue-level connection endpoints are shown separately when available.

Not linked

ATLPC0012633