- Route
- oral
- Form
- Kit
- Holder
- Azurity Pharmaceuticals, Inc
- Scope
- Direct label match
Vancomycin
ATLPD0000105
Product-level evidence profile for identity and molecular form, PK exposure, clinical context, safety context, label material, and reproducible data access.
- ADMETatlas IDATLPD0000105
- Peptide-link statusDefined molecular entity
- Linked peptides1
- Product routenot established
- PK summaries10
- Trial references25
- Matched label records88
- Regulatory-label PK7
Product evidence profile
Product identity and molecular form, PK exposure evidence, safety context, clinical and label context, interpretation boundaries, and reproducibility exits available for this product.
What is this product, which peptide does it map to, and what is its structure?
What is the drug used for and how does it act?
Are there curated exposure / PK summaries or cited observations?
What safety, postmarketing, and immune-recognition signals surround the product?
What trial and product-label context is attached to this product?
How is the evidence scoped, traced, cited, and reopened?
One. Molecular identity & structure
What the product is, how its complete molecular form is defined, and which chemical or structural representations support that identity.
Identity
Vancomycin
ATLPD0000105This product identity anchors product-level label, trial, postmarketing, and PK context. Route, form, and holder fields are shown when they are normalized from product or label references, not inferred from the product name.
- Product name
- Vancomycin
- ADMETatlas product ID
- ATLPD0000105
- Aliases / marketed names
- No additional aliases
These anchors support product-level lookup and context attachment. They are identity evidence, not ADMET endpoint measurements.
ATC classification © WHO Collaborating Centre for Drug Statistics Methodology; used unmodified for non-commercial research.
Label formulation evidence
- Route
- intravenous
- Form
- Injection, powder, lyophilized, for solution
- Holder
- Rebel Distributors Corp
- Scope
- Direct label match
- Route
- intravenous
- Form
- Injection, solution
- Holder
- Hikma Pharmaceuticals USA Inc.
- Scope
- Direct label match
- Route
- oral
- Form
- Capsule
- Holder
- Ani Pharmaceuticals, Inc.
- Scope
- Direct label match
- Route
- oral
- Form
- Solution
- Holder
- Wilshire Pharmaceuticals, Inc.
- Scope
- Direct label match
- Route
- intravenous
- Form
- Injection
- Holder
- Xellia Pharmaceuticals Aps
- Scope
- Direct label match
- Route
- intravenous; oral
- Form
- Injection
- Holder
- Hikma Pharmaceuticals USA Inc.
- Scope
- Direct label match
- Route
- intravenous; ocular
- Form
- Injection, solution
- Holder
- Baxter Healthcare Corporation
- Scope
- Direct label match
| Label / formulation | Route | Form | Holder | Context | Reference |
|---|---|---|---|---|---|
FIRVANQ (VANCOMYCIN HYDROCHLORIDE) KIT [AZURITY PHARMACEUTICALS, INC] Dec 17, 2025 | oral | Kit | Azurity Pharmaceuticals, Inc | Direct label match | DailyMed record |
STERILE VANCOMYCIN HYDROCHLORIDE (VANCOMYCIN HYDROCHLORIDE) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION [REBEL DISTRIBUTORS CORP] Apr 14, 2011 | intravenous | Injection, powder, lyophilized, for solution | Rebel Distributors Corp | Direct label match | DailyMed record |
TYZAVAN (VANCOMYCIN) INJECTION, SOLUTION [HIKMA PHARMACEUTICALS USA INC.] Nov 17, 2025 | intravenous | Injection, solution | Hikma Pharmaceuticals USA Inc. | Direct label match | DailyMed record |
VANCOCIN (VANCOMYCIN HYDROCHLORIDE) CAPSULE [ANI PHARMACEUTICALS, INC.] Dec 23, 2025 | oral | Capsule | Ani Pharmaceuticals, Inc. | Direct label match | DailyMed record |
VANCOMYCIN HYDROCHLORIDE FOR ORAL SOLUTION (VANCOMYCIN HYDROCHLORIDE) KIT [WILSHIRE PHARMACEUTICALS, INC.] Dec 18, 2025 | oral | Solution | Wilshire Pharmaceuticals, Inc. | Direct label match | DailyMed record |
VANCOMYCIN HYDROCHLORIDE INJECTION [XELLIA PHARMACEUTICALS APS] Feb 04, 2016 | intravenous | Injection | Xellia Pharmaceuticals Aps | Direct label match | DailyMed record |
VANCOMYCIN HYDROCHLORIDE INJECTION, POWDER, FOR SOLUTION [HIKMA PHARMACEUTICALS USA INC.] Aug 18, 2025 | intravenous; oral | Injection | Hikma Pharmaceuticals USA Inc. | Direct label match | DailyMed record |
VANCOMYCIN HYDROCHLORIDE INJECTION, SOLUTION [BAXTER HEALTHCARE CORPORATION] Mar 18, 2026 | intravenous; ocular | Injection, solution | Baxter Healthcare Corporation | Direct label match | DailyMed record |
Record-set scope (88 matched labels)
The table shows 8 representative records across route, formulation, direct/combination context, and identified veterinary status. The complete 88-record set remains available in the structured product profile.
Linked peptide identity
Product-level label, safety, trial, and PK context may be read beside the linked peptide identity. Endpoint truth still remains controlled by endpoint-specific evidence and compatibility rules.
The public link view emphasizes sequence, identity role, reference support, and interpretation boundary rather than non-public peptide identifiers.
- Identity role
- Reference identity
- Sequence
- Open peptide profile for sequence
- Residue length
- Open peptide profile
- Reference support
- 1 supporting reference
Multiple linked identities can reflect reviewed source-sequence differences, variant entries, or precursor-like entries. Use the reference identity as the main product-context link.
Source matching trace1 record
| Identity match | Reference | Link review |
|---|---|---|
| Reference identity | Evidence context | Linked peptide identity |
The link supports product-context interpretation beside a peptide identity. It is not a measured endpoint, and it does not promote label, safety, or trial context into peptide-level endpoint truth by itself.
C[C@H]1[C@H]([C@@](C[C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)[C@H]([C@H](C(=O)N[C@H](C(=O)N[C@H]5C(=O)N[C@@H]7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9O)O)[C@H](NC(=O)[C@H]([C@@H](C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)CC(=O)N)NC(=O)[C@@H](CC(C)C)NC)O)Cl)CO)O)O)(C)N)OStructure shown for the reviewed peptide identity linked to this product (ATLPC0035831). Atom-level 2D depiction rendered from the reviewed SMILES.
A 2D graph describes connectivity, not conformation; a 3D reference describes one coordinate model, not the full ensemble.
Open linked peptide · ATLPC0035831Two. Pharmacology: indication & mechanism
What the drug is used for and how it acts, based on curated therapeutic indications and mechanism-of-action evidence for the product identity.
Indication & mechanism of action
Three. Pharmacokinetics & exposure
Traceable exposure and PK properties across product labels, literature, and nonclinical evidence.
Pharmacokinetics & exposure
Exposure values for the complete product as tested.
Traceable exposure properties
Human product-label values are shown first, followed by additional source-backed evidence.
Human exposure properties reported in official product labeling.
Other source-backed PK properties across labels, literature, and nonclinical studies.
Direct source values extend the product's PK endpoint profile.
Cited measurement trace11 observations
- Context
- oral
- Measured material
- Whole product
- Evidence role
- Source-reported observation
- Reference
- Source record
- Context
- rat · oral · plasma
- Measured material
- Whole product
- Evidence role
- Curated comparable measurement
- Reference
- Reference
- Context
- beagle dog · oral · plasma
- Measured material
- Whole product
- Evidence role
- Curated comparable measurement
- Reference
- Reference
- Context
- beagle dog · oral · plasma
- Measured material
- Whole product
- Evidence role
- Curated comparable measurement
- Reference
- Reference
- Context
- human · plasma · subjects with normal kidney function
- Measured material
- Reported analyte
- Evidence role
- Source-reported product-label value
- Reference
- Reference
- Context
- human · plasma · subjects with normal kidney function
- Measured material
- Reported analyte
- Evidence role
- Source-reported product-label value
- Reference
- Reference
- Context
- human · intravenous · 1 g · plasma · subjects with normal kidney function
- Measured material
- Reported analyte
- Evidence role
- Source-reported product-label value
- Reference
- Reference
- Context
- human · 500 mg · plasma · subjects with normal kidney function
- Measured material
- Reported analyte
- Evidence role
- Source-reported product-label value
- Reference
- Reference
- Context
- human · plasma
- Measured material
- Reported analyte
- Evidence role
- Source-reported product-label value
- Reference
- Reference
- Context
- human · intravenous · 1 g · plasma · subjects with normal kidney function
- Measured material
- Reported analyte
- Evidence role
- Source-reported product-label value
- Reference
- Reference
| PK property | Value | Context | Reference | Measured material | Evidence role | Reported statement |
|---|---|---|---|---|---|---|
| Bioavailability | <10 % | oral | Source record | Whole product | Source-reported observation | Reference entry retained for traceability. |
| Bioavailability | 0.069 % | rat · oral · plasma | Reference | Whole product | Curated comparable measurement | Reference entry retained for traceability. |
| Bioavailability | 0.27 % | beagle dog · oral · plasma | Reference | Whole product | Curated comparable measurement | Reference entry retained for traceability. |
| Bioavailability | 1.66 % | beagle dog · oral · plasma | Reference | Whole product | Curated comparable measurement | Reference entry retained for traceability. |
| Clearance | ≈0.058 L/kg/h | human · plasma · subjects with normal kidney function | Reference | Reported analyte | Source-reported product-label value | Elimination Mean plasma clearance is about 0.058 L/kg/h, and mean renal clearance is about 0.048 L/kg/h. |
| Clearance | ≈0.048 L/kg/h | human · plasma · subjects with normal kidney function | Reference | Reported analyte | Source-reported product-label value | Elimination Mean plasma clearance is about 0.058 L/kg/h, and mean renal clearance is about 0.048 L/kg/h. |
| Cmax | ≈63 μg/mL | human · intravenous · 1 g · plasma · subjects with normal kidney function | Reference | Reported analyte | Source-reported product-label value | 12.3 Pharmacokinetics In subjects with normal kidney function, multiple intravenous dosing of 1 g of vancomycin (15 mg/kg) infused over 60 minutes produces mean plasma concentrations of approximately 63 mcg/mL immedia... |
| Cmax | ≈49 μg/mL | human · 500 mg · plasma · subjects with normal kidney function | Reference | Reported analyte | Source-reported product-label value | Multiple dosing of 500 mg infused over 30 minutes produces mean plasma concentrations of about 49 mcg/mL at the completion of infusion, mean plasma concentrations of about 19 mcg/mL 2 hours after infusion, and mean pl... |
| PPB | ≈55 % | human · plasma | Reference | Reported analyte | Source-reported product-label value | Vancomycin is approximately 55% serum protein bound as measured by ultrafiltration at vancomycin serum concentrations of 10 to 100 mcg/mL. |
| Tmax | 3,600 seconds | human · intravenous · 1 g · plasma · subjects with normal kidney function | Reference | Reported analyte | Source-reported product-label value | 12.3 Pharmacokinetics In subjects with normal kidney function, multiple intravenous dosing of 1 g of vancomycin (15 mg/kg) infused over 60 minutes produces mean plasma concentrations of approximately 63 mcg/mL immedia... |
How PK values are grouped
Summaries keep species, unit, route, dose, matrix, population, and source context separate. Whole-product values stay attached to the complete product.
Four. Safety & immunogenicity
Regulatory safety warnings, postmarketing and nonclinical safety context, and immune-recognition context. These describe available signals, not incidence rates or causality.
Safety & immunogenicity
Five. Clinical & regulatory evidence
Clinical-trial context and structured product-label references attached by product identity.
Clinical & regulatory evidence
Six. Provenance, scope & access
How to read, trace, cite, and reopen this profile: evidence scope, reference lineage, and reproducible data access.
Evidence scope
Evidence roles stay separate before interpretation
Endpoint summaries, product-context lanes, identity links, and source references answer different questions. This boundary keeps the page useful without converting context into stronger claims than the current review layer supports.
Compare PK results only when endpoint and experimental context are compatible.
Label, trial, safety, immune, and nonclinical records remain contextual unless separately extracted as an endpoint.
Defined molecular entity
Detailed interpretation and provenance guidance
Comparable measurement layer
Endpoint-level interpretation when context fields match.
Pooled product parameters across mismatched species, units, route, dose, matrix, population, or source context.
Clinical, label, safety, immune, and nonclinical context
Reading the product's evidence surroundings and source-backed context lanes.
Incidence rates, causality claims, product safety ranking, or normalized ADMET endpoint values.
Molecular identity context
Reading product context beside a reviewed peptide identity.
Automatic transfer of every product-level signal to peptide-level endpoint evidence.
Reproducibility and source trace
Checking where labels, trials, safety reports, identity links, and curated measurements came from.
A substitute for normalized evidence, context grouping, or endpoint review.
Original-source reading path
Reading the source reference in its native regulatory, registry, literature, or source context.
Bypassing ADMETatlas curation status, interpretation boundaries, or endpoint-promotion policy.
Reference lineage
Source families are separated by scientific role
Label, trial, safety, immune, identity-link, and PK evidence enter the product profile through different review paths. This module keeps their roles visible so users can trace evidence without over-reading context counts.
active reference families
source-matching traces
PK plus context entries
current product profile
Regulatory product-label context
Label sections, label-derived PK statements, safety wording, route, formulation, and immunogenicity context when extracted.
Label material supports product context. It becomes endpoint evidence only through the reviewed PK or endpoint extraction path.
Human study-registration context
Trial identity, phase/status, intervention matching, and availability of results context around the product.
Trial registry entries are study context unless endpoint-compatible results are extracted and reviewed separately.
Safety surveillance context
Signal-aware reading of reported adverse-event context around marketed products.
Report counts do not establish causality, incidence, or comparative product safety.
Assay and nonclinical support context
Immune-recognition assays, nonclinical safety context, and neighboring signals that help interpret the product profile.
These entries are not clinical incidence or endpoint truth unless a review policy promotes a specific endpoint.
Named-product identity support
Matching named and dosed product presentations to a stable medication identity.
Identity records do not provide an endpoint value, administration outcome, or route-specific clinical result.
Source-matching and identity-review context
Source records used to assess product-to-peptide identity relationships and retained audit context.
Only an exact match to the current authoritative canonical identity supports a linked identity; all other traces remain product context.
Endpoint measurement trace
Rechecking source values, units, route, dose, matrix, population, and source context for PK summaries.
PK entries remain context-bound measurements and should not be pooled across incompatible contexts.
Link references and selected label entries carry direct source links. Product-context entries may instead carry source labels and curated summaries in the structured profile. Both are provenance, but only direct reference fields should be displayed as citation links.
Data access & citation
The structured profile access reopens the same product view used by this page, including molecular identity, PK evidence, product context, and reference lineage for the current public release.
public product profile
identity link scope
cited measurement trace
25 context · 2 identity support
label plus link traces
Use the product profile access for product-specific reproducibility. Use full-release downloads for catalog-scale analysis, with the current source policy and data dictionary.
Current product
Machine-readable profile for molecular identity, PK evidence summaries, product context, and reference lineage.
Uses the public ATL product ID in the URL. Non-public product identifiers remain outside the navigation label.
The request returns the structured product profile used by this page. It is the current product-specific reproducibility path while product-only tabular exports remain a release follow-up.
curl -sS 'https://admetatlas.scbdd.com/api/v1/products/ATLPD0000105' \
-H 'accept: application/json' \
-H 'X-Visibility: public_release'Use this module to reproduce the current product profile and locate full-release exports. Cross-product comparison still depends on compatible endpoint, species, route, dose, matrix, population, source, identity-link, and review context.