In 5 patients with severe renal impairment (CrCl<30 mL/minute), the AUC and T 1/2 of teriparatide were increased by 73% and 77%, respectively.
Evidence role
Reported: reviewed reported observation that should not be pooled as a comparable value yet
Assay / model
human
Condition
Teriparatide · aae667c5-381f-4f92-93df-2ed6158d07b0 · 12.3 Pharmacokinetics · teriparatide severe renal impairment auc increase text · In 5 patients with severe renal impairment (...