A 30-minute infusion resulted in a similar AUC 0-INF , but 2- to 3-fold lower C max than that observed with a 2- to 10-minute infusion at the same dose.
Evidence role
Reported: reviewed reported observation that should not be pooled as a comparable value yet
Assay / model
human
Condition
Carfilzomib · ea66eb30-e665-4693-99a1-a9d3b4bbe2d6 · 12.3 Pharmacokinetics · cmax auc infusion duration comparison text · A 30-minute infusion resulted in a similar AUC 0-INF , bu...