Clearance evidence

Peptide

ATLPC0006669

Measured material

Specific molecular form

Endpoint

Clearance

ADMET domain

Excretion / Persistence

Value

Observation

the total plasma clearance of daptomycin normalized to total body weight was approximately 15% lower in moderately obese subjects and 23% lower in extremely obese subjects than in nonobese controls.

Evidence role

Reported: reviewed reported observation that should not be pooled as a comparable value yet

Assay / model

human · plasma

Condition

Daptomycin · 1957b6ce-7382-4a7b-bf02-3595948d09c6 · 12.3 Pharmacokinetics · daptomycin obesity clearance lower text · the total plasma clearance of daptomycin normalized to total...

Scientific source

DailyMed

Open source

Clearance evidence

Developability

Resources

Measurement