ADMETatlas — Peptide ADMET Evidence Atlas

Evidence entries

581records·423peptides

Showing reference-linked Protease stability evidence with reported value, assay context, interpretation role, and reference access kept separate.

Assay context

Evidence role

All581 Curated comparable515 Reported66

#	Endpoint	Peptide		Assay context	Evidence role	Reference
1	Protease stability Metabolic & Proteolytic Stability	ATLPC0014631	2 hours 7,200 seconds	RP-HPLCTrypsin1 mg/mL	Comparable	Open
2	Protease stability Metabolic & Proteolytic Stability	ATLPC0029064	0.003 seconds	Proteolysis assayMurine crude intestinal protease preparetion120 minutes67 pico molar	Comparable	Open
3	Protease stability Metabolic & Proteolytic Stability	ATLPC0033358	1.138 seconds	Proteolysis assayMurine crude intestinal protease preparetion120 minutes67 pico molar	Comparable	Open
4	Protease stability Metabolic & Proteolytic Stability	ATLPC0013949	0.026 seconds	Proteolysis assayMurine crude intestinal protease preparetion120 minutes67 pico molar	Comparable	Open
5	Protease stability Metabolic & Proteolytic Stability	ATLPC0030748	0.05 seconds	Proteolysis assayMurine crude intestinal protease preparetion120 minutes67 pico molar	Comparable	Open
6	Protease stability Metabolic & Proteolytic Stability	ATLPC0011420	Observation 630 ± 30 ( Deamidation Half Life)	LC-MSWild-type and mutant MBP samples were collected after 1, 3, 6, 9, and 12 and 1, 3, 5, 7, 9, and 12 calendar months,pH 7.0 at 23 ± 2C20 μM	Reported	Open
7	Protease stability Metabolic & Proteolytic Stability	ATLPC0024611	Observation 12 ± 1 (Deamidation Half Life)	LC-MSWild-type and mutant MBP samples were collected after 1, 3, 6, 9, and 12 and 1, 3, 5, 7, 9, and 12 calendar months,pH 7.0 at 23 ± 2C20 μM	Reported	Open
8	Protease stability Metabolic & Proteolytic Stability	ATLPC0020899	0.025 seconds	Proteolysis assayMurine crude intestinal protease preparetion120 minutes67 pico molar	Comparable	Open
9	Protease stability Metabolic & Proteolytic Stability	ATLPC0006310	0.11 seconds	Proteolysis assayMurine crude intestinal protease preparetion120 minutes67 pico molar	Comparable	Open
10	Protease stability Metabolic & Proteolytic Stability	ATLPC0031241	67 hours 241,200 seconds	RP-HPLCTrypsin1 mg/mL	Comparable	Open
11	Protease stability Metabolic & Proteolytic Stability	ATLPC0031241	67 hours 241,200 seconds	RP-HPLCTrypsin1 mg/mL	Comparable	Open
12	Protease stability Metabolic & Proteolytic Stability	ATLPC0016350	0.006 seconds	Proteolysis assayMurine crude intestinal protease preparetion120 minutes67 pico molar	Comparable	Open
13	Protease stability Metabolic & Proteolytic Stability	ATLPC0010077	1.234 seconds	Proteolysis assayMurine crude intestinal protease preparetion120 minutes67 pico molar	Comparable	Open
14	Protease stability Metabolic & Proteolytic Stability	ATLPC0014631	0.6 hours 2,160 seconds	RP-HPLCTrypsin1 mg/mL	Comparable	Open
15	Protease stability Metabolic & Proteolytic Stability	ATLPC0026136	3 Hours 10,800 seconds	RP-HPLCPBS solutionAliquots (100 μL) were taken at 0, 0.5, 1, 2, 3, 4, 5, 6, and 24 h time points1 mM	Comparable	Open
16	Protease stability Metabolic & Proteolytic Stability	ATLPC0020762	0.035 seconds	Proteolysis assayMurine crude intestinal protease preparetion120 minutes67 pico molar	Comparable	Open
17	Protease stability Metabolic & Proteolytic Stability	ATLPC0008617	38.6 minutes 2,316 seconds	Trypsin degradation assay, Analytical reverse phase HPLCSolutions of bovine trypsin and the peptide or PEG -peptide conjugate in 10 mM PBS (pH 7.4)bovine20μM	Comparable	Open
18	Protease stability Metabolic & Proteolytic Stability	ATLPC0003338	0.002 seconds	Proteolysis assayMurine crude intestinal protease preparetion120 minutes67 pico molar	Comparable	Open
19	Protease stability Metabolic & Proteolytic Stability	ATLPC0015137	0.546 seconds	Proteolysis assayMurine crude intestinal protease preparetion120 minutes67 pico molar	Comparable	Open
20	Protease stability Metabolic & Proteolytic Stability	ATLPC0021851	0.037 seconds	Proteolysis assayMurine crude intestinal protease preparetion120 minutes67 pico molar	Comparable	Open

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Measurements

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Evidence entries