Evidence — ADMETatlas

Evidence entries

1,032records·502linked peptides

Showing reference-linked Serum/plasma stability evidence with reported value, assay context, interpretation role, and reference access kept separate.

Assay context

Evidence role

All1,032 Curated comparable883 Reported149

#	Endpoint	Measured entity		Assay context	Evidence role	Reference
1	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0028313 Specific molecular form	6 hours 21,600 seconds	HPLCMouse serum + 1μM catroprilmouse4 X lO-7M, 10 μCi	Comparable	Reference
2	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0013052 Specific molecular form	777.0 ± 10.2 Minutes 46,620 seconds	RP-HPLCMouse serummouse6 nmol	Comparable	Reference
3	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0001877 Specific molecular form	30,240 seconds	Standard assayMice plasmamouseIV	Comparable	Reference
4	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0022176 Specific molecular form	73 Minutes 4,380 seconds	HPLCHuman serumhuman2 μg/μl	Comparable	Reference
5	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0001635 Specific molecular form	Observation Slightly lower stability than TXIB	RP-UPLCMale AB human serumhumanAliquots of each peptide were taken out at 0, 12, 24, 36, and 48 h.100 μM	Reported	Reference
6	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0032792 Specific molecular form	4,740 seconds	stability25% aqueous mouse serummouse	Comparable	Reference
7	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0027791 Specific molecular form	84.6 Hours 304,560 seconds	RP-HPLCHuman blood plasmahuman0.00001 M	Comparable	Reference
8	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0014180 Specific molecular form	21,240 seconds	stability	Reported	Reference
9	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0026977 Specific molecular form	150 minutes 9,000 seconds	MALDI-TOF-MS25% mouse serummouse30-480 Minutes7.5 μg/100μl	Comparable	Reference
10	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0031376 Specific molecular form	Observation Medium Stable	RP-HPLCMouse blood/plasma/serummouseAliquots (20 or 40 μL) taken after 0 and 60 min (0, 10 and 30 min for Api88)31.5 μmol/L	Reported	Reference
11	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0033098 Specific molecular form	9,900 seconds	1H-NMRHuman blood plasmahuman2-3 mg/ml	Comparable	Reference
12	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0006189 Specific molecular form	136,116 seconds	HPLC1 mL mouse serummouseAt 0, 0.08, 0.16, 0.33, 0.5, 1, 2, 6, 12, 24, 48, 72 h, adding 40 μL termination solution1 mg/ml	Comparable	Reference
13	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0022157 Specific molecular form	174 ±7 minute 10,440 seconds	MALDI-TOF-MSRat serumrat1.07mM	Comparable	Reference
14	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0015923 Specific molecular form	11.3 ±0.4 minute 678 seconds	TLCHuman plasma mixed with drug Thiothixenehuman2, 4, 6, 10, 30, 60 and 90, 180 minutes10^-8 M	Comparable	Reference
15	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0022323 Specific molecular form	10.4 ±1.1 minutes 624 seconds	Radioimmunoassay and HPLCPancreatitis patient plasma1.6pmol	Comparable	Reference
16	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0015923 Specific molecular form	2.17 ±0.05 minutes 130.2 seconds	TLC with radiometric quantification of [3H]-Leu-enkephalin degradation productshuman serum	Comparable	Reference
17	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0022697 Specific molecular form	30 Hours 108,000 seconds	ELISADiabetic rats serumrat5 nmol	Comparable	Reference
18	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0010187 Specific molecular form	2.4 ±0.7 minutes 144 seconds	RadioimmunoassayHuman blood plasmahuman	Comparable	Reference
19	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0018604 Specific molecular form	11.9 ±0.7 hours 42,840 seconds	Radioimmunoassay and HPLCFemale pigs plasma+ Peptide sample+ DPP-IV inhibitor (valine pyrrolidide) + aprotininporcine	Comparable	Reference
20	Serum/plasma stability Metabolic & Proteolytic Stability	Peptide ATLPC0025294 Specific molecular form	67 minutes 4,020 seconds	RP-HPLCMouse serummouse100 μg/mL	Comparable	Reference

1–20 / 1,032

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