Peptide·plain sequence-like

Carperitide

ATLPC0035843

H-Ser-Leu-Arg-Arg-Ser-Ser-Cys(1)-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser…

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Length
31 aa

Coveragecounts only · not riskATLPC0035843

Measurements
1
Endpoints
1
Domains
1/5
Products
1

No matrix stability evidence
No clearance evidence
Product-level review pending
No sequence liability cues

Jump to domain

Open the matching evidence section below

All evidence index · 1

Exposure / Absorption

No evidence

Distribution / Barrier

1 measurement

Metabolic & Proteolytic Stability

No evidence

Excretion / Persistence

No evidence

Toxicity / Safety

No evidence

Sequence & molecular identity

1 forms

Reviewed sequence, peptidoform forms, chemical representation, 3D references, and covalent topology used to interpret this peptide identity.

Sequence & peptidoform

Identity view

A peptidoform is one specific molecular form of the peptide — its sequence plus the modifications at given positions (HUPO-PSI term). This view preserves the reported terminal groups, residue modifications, and stereo markers from the source notation.

H-Ser-Leu-Arg-Arg-Ser-Ser-Cys(1)-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys(1)-Asn-Ser-Phe-Arg-Tyr-OH

Identity summarySpecific molecular form represented

Identity status: Specific molecular form represented
Residues: 31
Peptidoform features: 2
Documented molecular forms: 1
Representations: 2

Documented molecular forms1 form linked to this peptide identity

Form	Topology	Modifications	Connections	Representations	Measurements
ATLPF0038985	—	4	1	1	1

Residue view

Residue display

31 residues

H1S2L3R4R5S6S7C8F9G10G11R12M13D14R15I16G17A18Q19S20G21L22G23C24N25S26F27R28Y29X30H31

Side-chain classNonpolarPolarBasic (+)Acidic (−)Modified

Soft tints mark standard side-chain classes for scanning. Primary emphasis is reserved for reported modifications, termini, secondary-structure tracks, and topology links.

Peptidoform features

Features are shown only when a reported notation or topology record supports them.

Non-standard residue tokenpos 30

Reported token O is not one of the 20 standard residue symbols in this display.

Residue modificationpos 21

Inline modification 1 is reported on parent residue G21.

Reported sequence notation was converted to parent-residue display for visualization; the original notation remains shown below.

Structure & chemistry

Chemical representationsequence / HELM only

Representation class

How the current release can interpret this identity chemically.

plain sequence-like

Parent-residue sequence

Residue string used for positional interpretation when available.

HSLRRSSCFGGRMDRIGAQSGLGCNSFRYXH

HELM

Polymer notation for modified peptide representation when available.

Not available

SMILES

Chemical graph string used for atom-level 2D depiction when available.

Not available

No atom-level graph

A reviewed SMILES is required before a 2D molecular depiction can be shown. Sequence and HELM remain useful for identity interpretation, but they do not replace a chemical graph.

3D structure referencesnone attached

3D structure not available

A 3D structure isn't available for this peptide in the current release. Chemistry and topology fields remain available when represented by sequence, HELM, or SMILES.

Covalent topology & modifications1 signal

Feature	Positions	Interpretation	Link
Form-level topology	ATLPF0038985	Disulfide-constrained form. Residue-level connection endpoints are shown separately when available.	Not linked

Physicochemical profile

6 descriptors

Computed sequence-derived descriptors and any measured physicochemical evidence such as lipophilicity. Computed values are interpretation aids, not experimental ADMET measurements.

Physicochemical descriptors unavailable

These descriptors require a standard parent-residue sequence. The module remains visible so modified or unresolved identities are not forced into unreliable computed values.

Computed developability descriptors

Deterministic descriptors computed from the reviewed sequence or chemical structure (RDKit), each anchored to a literature method. These are computed estimates for developability interpretation — not experimental measurements — and are validated against independent reference implementations.

Structure-derived (developability)

Computed from the representative peptidoform's chemical structure. Rule-of-5 / beyond-Ro5 framing per Lipinski/Doak.

Topological polar surface area

1403.4 Å²

Computed logP (Crippen)

-19.72

Computed logP — distinct from the measured logD endpoint.

Hydrogen-bond donors

Hydrogen-bond acceptors

Rotatable bonds

Rule-of-5 / beyond-Ro5 flags

Beyond bRo5

3 Ro5 violations · MW 3,080.5 Da

Distribution / Barrier

1 records

What is known about distribution, binding, permeability, or barrier crossing?

Evidence records

Complete canonical measurements and observations attached to this domain.

Endpoint scope

Formal ADMET endpoints represented for this peptide.

Matched-context analysis

Quantitative results that may be analysed only with scientifically compatible records.

Reported-result review

Qualitative, narrative, or review-first results interpreted in their source context.

Endpoints in scopePlasma protein binding

Evidence interpretation

Result type, analysis use, and source-check status are kept separate so a numerical value is not mistaken for a universally comparable result.

Eligible for matched-context analysis

Quantitative results whose endpoint and context must still be matched before analysis.

Interpret as reported

Qualitative, narrative, or review-first findings preserved in source context.

Supporting context only

Reference, label, clinical, or supporting context for interpretation.

Review before analysis

Records whose present structure does not establish a safe analysis role.

Evidence by endpoint

Rows are grouped by endpoint so value, assay context, interpretation layer, and reference can be checked in place.

Plasma protein binding1 record · 1 matched-context · 0 as reported · 0 context only · 0 review required

#	Value	Analysis use	Assay / model	Result context	Reference
1	~ 10 %	Eligible when experimental context matches	rat · rat plasma	Result: Approximate quantitative measurement · Molecular form: ATLPF0038985 · Source: Primary reference linked	Reference

Barrier and permeability assay context

PAMPA, Caco-2, MDCK/RRCK, and BBB findings are assay/model contexts under Distribution / Barrier. They should not be read as interchangeable measurements.

PAMPA

artificial membrane

Caco-2

cell monolayer

MDCK

cell monolayer

RRCK

cell monolayer

BBB

barrier evidence

Evidence landscape

1 records

Cross-domain evidence distribution and measurement-level detail; the domain modules above show evidence in context, and every row remains available for audit here.

Evidence landscape

A cross-domain view of evidence volume, scientifically permitted analysis use, and source traceability.

ADMET domain

Eligible when context matches

Interpret as reported

Supporting context only

Review before analysis

Exposure / Absorption

0 evidence records

Distribution / Barrier

1 evidence record

Metabolic & Proteolytic Stability

0 evidence records

Excretion / Persistence

0 evidence records

Toxicity / Safety

0 evidence records

Endpoint distribution

Top evidence-bearing endpoint questions.

Plasma Protein Binding

Assay context

Broad context buckets, useful before comparing values.

In vivo / route

Traceability

Reference-link availability for measurement-level audit.

Linked reference

Not linked

All evidence index

Every evidence record remains available for audit and drilldown. Counts describe evidence volume, not confidence.

DomainAnalysis useReference

#	ADMET domain	Endpoint	Reported value	Result type	Analysis use	Assay / model	Condition	Reference
1	Distribution / Barrier Distribution	Plasma Protein Binding	~ 10 %	Approximate quantitative measurement	Eligible when experimental context matches	rat · rat plasma	Not specified	Reference Primary reference linked

1–1 / 1

Product context

1 products

Product-level route, label, and clinical context that frames peptide-level evidence. A peptide-level summary only; product pages keep the full drilldown.

Summary1 linked product

Linked products: 1
Label context: None
Clinical trials: 3
Safety label cues: None

Linked products1 shown

Carperitide

Peptide-product match

Reviewed peptide match

Route / product class

Not resolved in this release

Clinical context

3 trial records · 1 exact intervention matches · latest 2016-11-08

Label safety context

No label safety cue linked

View product

Identity & reference map

1 sources

Reference-level support for checking reported names, sequence notation, and peptide identity agreement.

Summary1 reference group

Identity type: modified or textual identity
Reported notation: 0
Reference groups: 1
Measurements: 1
ATL peptide ID: ATLPC0035843

Identity concordance

Exact reported notation

Reported sequence string matches the current peptide notation.

0 / 1

Parent-residue compatible

Reported notation differs, but resolves to the same parent-residue display.

0 / 1

Different notation

Reported notation does not resolve to the current display sequence.

0 / 1

Source sequence not captured

No source-specific sequence was captured for comparison; this is not interpreted as agreement or disagreement.

1 / 1

Reported sequence notation

No source-specific sequence notation has been captured in the current identity references.

Current identity

H-Ser-Leu-Arg-Arg-Ser-Ser-Cys(1)-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys(1)-Asn-Ser-Phe-Arg-Tyr-OH

Reported names

No distinct human-readable aliases are exposed.

Reference map1 reference group

Reference map

Grouped by reference link, with endpoint scope and reported identity kept visible.

Reference	Supports	Reported identity	Records
Reference Open	Distribution Plasma Protein Binding	No reported alias	1 identity 1 evidence

Data access & reproducibility

Stable record access, analysis-ready files, and scripted retrieval for reproducing this profile view.

Record scopePublic release

ATL peptide ID: ATLPC0035843
Identity type: modified or textual identity
ADMET endpoints: 1
Evidence records: 1
Reference groups: 1
Release view: Public release

Data access

Structured peptide profile

JSON

Peptide-specific profile used by this page, including identity and evidence context.

Open JSON

Peptide catalogue

TSV

Complete frozen peptide table. Filter the ATL peptide ID column locally to isolate this record.

Download catalogue

Measurement catalogue

TSV

Complete frozen measurement table. Join or filter by ATL peptide ID for peptide-level analysis.

Download measurements

Programmatic access

The request returns the same structured peptide record used by this profile. The tabular downloads are complete frozen release tables and should be filtered locally by ATL peptide ID.

Open endpoint

GET /api/v1/peptides/ATLPC0035843

open

curl -sS 'https://admetatlas.scbdd.com/api/v1/peptides/ATLPC0035843' \
  -H 'accept: application/json' \
  -H 'X-Visibility: public_release'

Form

Topology

Modifications

Connections

Representations

Measurements

ATLPF0038985

—

Feature

Positions

Interpretation

Link

Form-level topology

ATLPF0038985

Disulfide-constrained form. Residue-level connection endpoints are shown separately when available.

Not linked

Value

Analysis use

Assay / model

Result context

Reference

~ 10 %

Eligible when experimental context matches

rat · rat plasma

Result: Approximate quantitative measurement · Molecular form: ATLPF0038985 · Source: Primary reference linked

Reference

ADMET domain

Endpoint

Reported value

Result type

Analysis use

Assay / model

Condition

Reference

Distribution / Barrier

Distribution

Plasma Protein Binding

~ 10 %

Approximate quantitative measurement

Eligible when experimental context matches

rat · rat plasma

Not specified

Reference

Primary reference linked

Reference

Supports

Reported identity

Records

Reference

Open

Distribution

Plasma Protein Binding

No reported alias

1 identity

1 evidence