tpsa · Ų
Sum of polar (N,O) surface contributions. Strong correlate of passive permeability and oral absorption. Exact match vs CycPeptMPDB precomputed.
Calculated from chemical structure (RDKit) when a peptide-scale SMILES is available (MW ≤ 10 kDa). Values appear on peptide records under the physicochemical profile.
Peptides with the highest values for this descriptor (of 14,327 computed). Each links to its peptide page.
| Peptide | Sequence | Value Ų |
|---|---|---|
| ATLPC0024530 | SQLGDLGSGAGQGGGGGGSIRAAGGAFGKLEA | 4189.36 |
| ATLPC0017292 | SQLGDLGSGAGQGGGGGGSIRAAGGAFGKLEA | 4189.36 |
| ATLPC0035611 | GWPAYPGPNGIRSSVCQTKLGCGKKNLATKGV | 3938.96 |
| ATLPC0021765 | MAFLKKSLFLVLFLGIVSLSICEEEKREGEEE | 3919.39 |
| ATLPC0024786 | MFTMKKSMLLIVLLGIISLSLCEQERNADEDE | 3757.08 |
| ATLPC0006307 | TDTNVIGECFDEWSRCHRQTRWWTKILFQSCE | 3741.96 |
| TDTNVIGECFDEWSRCHRQTRWWTKILFQSCE |
| 3741.96 |
| ATLPC0026628 | MFTLKKSLFLVLILGMVSLSLCQQESNADKET | 3674.27 |
| ATLPC0016028 | MAFLKKSLFLVLFLGLVSLSMCEEEKRENEVE | 3624.25 |
| ATLPC0011933 | MQFTKLATVLIVSLMGSAAIAAPSVDNAPAVA | 3597.75 |
| ATLPC0022593 | MQIFVKTLTGKTITLEVEPSDTIENVKAKIQD | 3597.22 |
| ATLPC0035489 | MQIFVKTLTGKTITLEVEPSDTIENVKAKIQD | 3597.22 |