Evidence — ADMETatlas

Evidence entries

1,990records·504linked peptides

Showing reference-linked Blood-brain barrier (BBB) evidence with reported value, assay context, interpretation role, and reference access kept separate.

Assay context

Evidence role

All1,990 Curated comparable646 Reported1,344

#	Endpoint	Measured entity		Assay context	Evidence role	Reference
1	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0021608 Peptide backbone	-0.079 min^-1 Unidirectional influx (Kin / PS product)	blood-brain barrier	Reported	Reference
2	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0000870 Peptide backbone	0.012 mL/g Brain–plasma partition (Kp)	blood-brain barrierIntravenous	Reported	Reference
3	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0035205 Peptide backbone	Observation in_vitro_result: 11.7+/- 6.4 apparent permeability; transport_type: can transport cargo	blood-brain barrierRat astrocyte	Reported	Reference
4	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0027334 Peptide backbone	23.8 min Uptake time	blood-brain barrier	Reported	Reference
5	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0035205 Peptide backbone	Observation in_vitro_result: 0.20+/- 0.01 transport efficiency; transport_type: can transport cargo	blood-brain barrierRat astrocyte	Reported	Reference
6	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0011617 Peptide backbone	0.032 %/g Brain uptake (%ID/g)	blood-brain barrierIntravenous	Reported	Reference
7	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0005540 Peptide backbone	Observation in_vitro_result: It shows the permeability towards the BBB.; transport_type: Receptor-mediated transcytosis	blood-brain barrierbEnd.3 cells	Reported	Reference
8	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0001081 Peptide backbone	0.056 min^-1 Unidirectional influx (Kin / PS product)	blood-brain barrier	Reported	Reference
9	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0031412 Peptide backbone	Observation in_vitro_result: 13.51 +/- 0.70; transport_type: Transmigration	blood-brain barrierbEND cell line	Reported	Reference
10	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0023555 Peptide backbone	82 % Brain uptake (%ID/g)	Not specified	Reported	Reference
11	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0021480 Peptide backbone	Observation in_vitro_result: 35% fluoroscence measured at 1 micromolar peptide concentration; transport_type: Transcytosis	blood-brain barrierHuman glioblastoma cell line U-87	Reported	Reference
12	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0032918 Peptide backbone	0.011 mL/g Brain–plasma partition (Kp)	blood-brain barrierIntravenous	Reported	Reference
13	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0009237 Peptide backbone	0.047 min^-1 Unidirectional influx (Kin / PS product)	blood-brain barrier	Reported	Reference
14	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0016267 Peptide backbone	0.023 mL/g Brain–plasma partition (Kp)	blood-brain barrierIntravenous	Reported	Reference
15	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0030952 Peptide backbone	77.5 % Brain uptake (%ID/g)	Not specified	Reported	Reference
16	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0027947 Peptide backbone	2.86 mL/g Brain–plasma partition (Kp)	blood-brain barrier	Reported	Reference
17	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0029497 Peptide backbone	84.53 % Brain uptake (%ID/g)	blood-brain barrier	Reported	Reference
18	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0001469 Peptide backbone	5.12 x 10^-4 mL/g/min Unidirectional influx (Kin / PS product)	blood-brain barrierIntravenous	Reported	Reference
19	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0010575 Peptide backbone	-1.95 Relative / unspecified	Not specified	Reported	Reference
20	Blood-brain barrier (BBB) Distribution / Barrier	Peptide ATLPC0008489 Peptide backbone	0.059 min^-1 Unidirectional influx (Kin / PS product)	blood-brain barrier	Reported	Reference

1–20 / 1,990

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