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Peptide·modified or textual

Semaglutide

ATLPC0011948

H-Aib-EGTFTSDVSSYLEGQAAKEFIAWLVRGRG

Routes
Compare in workbenchDownload releaseAPI JSON
  • Length
    31 aa
On this page
  • 01 Sequence & molecular identity
  • 02 Physicochemical profile
  • 03 Exposure / Absorption
  • 04 Distribution / Barrier
  • 05 Metabolic & Proteolytic Stability
  • 06 Excretion / Persistence
  • 07 Evidence landscape
  • 08 Product context
  • 09 Identity & reference map
  • 10 Data access & reproducibility
Coveragecounts only · not riskATLPC0011948
  • Measurements
    73
  • Endpoints
    9
  • Domains
    4/5
  • Products
    1
  • 1 stability measurement
  • 47 clearance measurements
  • Product-level review pending
  • No sequence liability cues
Jump to domain

Open the matching evidence section below

All evidence index · 73
Exposure / Absorption
16 measurements
Distribution / Barrier
9 measurements
Metabolic & Proteolytic Stability
1 measurement
Excretion / Persistence
47 measurements
Toxicity / Safety
No evidence
01

Sequence & molecular identity

2 forms

Reviewed sequence, peptidoform forms, chemical representation, 3D references, and covalent topology used to interpret this peptide identity.

Sequence & peptidoform

·
Identity view

A peptidoform is one specific molecular form of the peptide — its sequence plus the modifications at given positions (HUPO-PSI term). This view preserves the reported terminal groups, residue modifications, and stereo markers from the source notation.

H-Aib-EGTFTSDVSSYLEGQAAKEFIAWLVRGRG
Identity summarySpecific molecular form represented
Identity status
Specific molecular form represented
Residues
31
Peptidoform features
1
Documented molecular forms
2
Representations
2
Documented molecular forms2 forms linked to this peptide identity
FormTopologyModificationsConnectionsRepresentationsMeasurements
ATLPF0013070———Notation only44
ATLPF0037366—4—222
Residue view
Residue display
31 residues
H1X2AibE3G4T5F6T7S8D9V10S11S12Y13L14E15G16Q17A18A19K20E21F22I23A24W25L26V27R28G29R30G31
Side-chain classNonpolarPolarBasic (+)Acidic (−)Modified

Soft tints mark standard side-chain classes for scanning. Primary emphasis is reserved for reported modifications, termini, secondary-structure tracks, and topology links.

Peptidoform features

Features are shown only when a reported notation or topology record supports them.

Non-standard residue tokenpos 2
Aib

Alpha-aminoisobutyric acid was reported as a non-standard residue. It is shown as X in the parent-residue display.

Reported sequence notation was converted to parent-residue display for visualization; the original notation remains shown below.

Structure & chemistry

·
Chemical representationsequence / HELM only
Representation class

How the current release can interpret this identity chemically.

modified or textual
Parent-residue sequence

Residue string used for positional interpretation when available.

HXEGTFTSDVSSYLEGQAAKEFIAWLVRGRG
HELM

Polymer notation for modified peptide representation when available.

Not available
SMILES

Chemical graph string used for atom-level 2D depiction when available.

Not available
No atom-level graph

A reviewed SMILES is required before a 2D molecular depiction can be shown. Sequence and HELM remain useful for identity interpretation, but they do not replace a chemical graph.

3D structure references10 references
Structure reference·
3D coordinates·Sequence matchexperimental
Sequence match·reference selected·identity 100.0%·confidence experimental
LinkMethodConfidenceMatch
OpenSequence matchexperimental100.0% identity
OpenSequence matchexperimental100.0% identity
OpenSequence matchexperimental100.0% identity
OpenSequence matchexperimental96.5% identity
OpenSequence matchexperimental96.5% identity
OpenSequence matchexperimental96.5% identity
OpenSequence matchexperimental96.5% identity
OpenSequence matchexperimental96.4% identity
OpenSequence matchexperimental96.4% identity
OpenSequence matchexperimental96.4% identity
Covalent topology & modifications1 signal
FeaturePositionsInterpretationLink
Form-level topologyATLPF0037366Open-chain form. Residue-level connection endpoints are shown separately when available.Not linked
02

Physicochemical profile

Computed sequence-derived descriptors and any measured physicochemical evidence such as lipophilicity. Computed values are interpretation aids, not experimental ADMET measurements.

Physicochemical descriptors unavailable

These descriptors require a standard parent-residue sequence. The module remains visible so modified or unresolved identities are not forced into unreliable computed values.

03

Exposure / Absorption

16 records

What evidence describes systemic exposure or absorption?

Evidence records
16
Complete canonical measurements and observations attached to this domain.
Endpoint scope
4
Formal ADMET endpoints represented for this peptide.
Matched-context in preview
0
Quantitative results that may be analysed only with scientifically compatible records.
Reported results in preview
0
Qualitative, narrative, or review-first results interpreted in their source context.
Endpoints in scopeAUCBioavailabilityCmaxTmax
Loading 16 Exposure / Absorption records…
04

Distribution / Barrier

9 records

What is known about distribution, binding, permeability, or barrier crossing?

Evidence records
9
Complete canonical measurements and observations attached to this domain.
Endpoint scope
2
Formal ADMET endpoints represented for this peptide.
Matched-context in preview
0
Quantitative results that may be analysed only with scientifically compatible records.
Reported results in preview
0
Qualitative, narrative, or review-first results interpreted in their source context.
Endpoints in scopePlasma protein bindingVd
Loading 9 Distribution / Barrier records…
Barrier and permeability assay context

PAMPA, Caco-2, MDCK/RRCK, and BBB findings are assay/model contexts under Distribution / Barrier. They should not be read as interchangeable measurements.

PAMPA
0

artificial membrane

Caco-2
0

cell monolayer

MDCK
0

cell monolayer

RRCK
0

cell monolayer

BBB
0

barrier evidence

05

Metabolic & Proteolytic Stability

1 records

How stable is the peptide in biological matrices or protease systems?

Evidence records
1
Complete canonical measurements and observations attached to this domain.
Endpoint scope
1
Formal ADMET endpoints represented for this peptide.
Matched-context in preview
0
Quantitative results that may be analysed only with scientifically compatible records.
Reported results in preview
0
Qualitative, narrative, or review-first results interpreted in their source context.
Endpoints in scopeSerum/plasma stability
Loading 1 Metabolic & Proteolytic Stability records…
06

Excretion / Persistence

47 records

What evidence describes clearance or persistence?

Evidence records
47
Complete canonical measurements and observations attached to this domain.
Endpoint scope
2
Formal ADMET endpoints represented for this peptide.
Matched-context in preview
6
Quantitative results that may be analysed only with scientifically compatible records.
Reported results in preview
13
Qualitative, narrative, or review-first results interpreted in their source context.
Endpoints in scopeHalf LifeClearance
Loading 47 Excretion / Persistence records…
07

Evidence landscape

73 records

Cross-domain evidence distribution and measurement-level detail. 20 of 73 evidence records are included in the profile preview; the full index is loaded below.

Loading 73 measurements…
08

Product context

1 products

Product-level route, label, and clinical context that frames peptide-level evidence. A peptide-level summary only; product pages keep the full drilldown.

·
Summary1 linked product
Linked products
1
Label context
1
Clinical trials
82
Safety label cues
None
Linked products1 shown

Semaglutide

OZEMPICWEGOVYRYBELSUS
Peptide-product match
Reviewed peptide match
Route / product class
Not resolved in this release
Clinical context
82 trial records · 32 exact intervention matches · 8 with results · latest 2026-04-21
Label safety context
Label linked
View product
09

Identity & reference map

73 sources

Reference-level support for checking reported names, sequence notation, and peptide identity agreement.

·
Summary15 reference groups
Identity type
reported modified sequence
Reported notation
1
Reference groups
15
Measurements
73
ATL peptide ID
ATLPC0011948
Identity concordance
Identity concordance
Exact reported notation

Reported sequence string matches the current peptide notation.

0 / 73
Parent-residue compatible

Reported notation differs, but resolves to the same parent-residue display.

2 / 73
Different notation

Reported notation does not resolve to the current display sequence.

0 / 73
Source sequence not captured

No source-specific sequence was captured for comparison; this is not interpreted as agreement or disagreement.

71 / 73
Reported sequence notation
Parent-compatible2 references
H-XEGTFTSDVSSYLEGQAAK-(XXEX)-EFIAWLVRGRG
Current identity
H-Aib-EGTFTSDVSSYLEGQAAKEFIAWLVRGRG
Reported names
No distinct human-readable aliases are exposed.
Reference map15 reference groups
Reference map

Grouped by reference link, with endpoint scope and reported identity kept visible.

ReferenceSupportsReported identityRecords
Reference
Open
Persistence
Half Life
No reported alias
23 identity
13 evidence
Reference
Open
Identity only
No reported alias
8 identity
0 evidence
Reference
Open
Identity only
No reported alias
8 identity
0 evidence
Reference
Open
Persistence
Half Life
No reported alias
4 identity
3 evidence
Reference
Open
Identity only
No reported alias
6 identity
0 evidence
Reference
Open
Identity only
No reported alias
5 identity
0 evidence
Reference
Open
Persistence
Half Life
No reported alias
4 identity
1 evidence
Reference
Open
Persistence
Half Life
No reported alias
3 identity
1 evidence
Reference
Open
Identity only
No reported alias
4 identity
0 evidence
Reference
Open
Persistence
Half Life
No reported alias
2 identity
1 evidence
1–10 / 15
10

Data access & reproducibility

Stable record access, analysis-ready files, and scripted retrieval for reproducing this profile view.

·
Record scopePublic release
ATL peptide ID
ATLPC0011948
Identity type
reported modified sequence
ADMET endpoints
9
Evidence records
73
Reference groups
15
Release view
Public release
Data access

Structured peptide profile

JSON

Peptide-specific profile used by this page, including identity and evidence context.

Open JSON

Peptide catalogue

TSV

Complete frozen peptide table. Filter the ATL peptide ID column locally to isolate this record.

Download catalogue

Measurement catalogue

TSV

Complete frozen measurement table. Join or filter by ATL peptide ID for peptide-level analysis.

Download measurements
Programmatic access

The request returns the same structured peptide record used by this profile. The tabular downloads are complete frozen release tables and should be filtered locally by ATL peptide ID.

Open endpoint
GET /api/v1/peptides/ATLPC0011948
open
curl -sS 'https://admetatlas.scbdd.com/api/v1/peptides/ATLPC0011948' \
  -H 'accept: application/json' \
  -H 'X-Visibility: public_release'
ADMETatlas
peptide evidence atlas

ADMETatlas is an open, curated atlas of ADMET evidence for therapeutic peptides — spanning developability, membrane permeability and blood–brain-barrier transport, immune-recognition context, and approved-product context. Every measurement stays linked to its original source, with stable identifiers and transparent curation, so results can be traced, cited, and reproduced.

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