ADMETatlas — Peptide ADMET Evidence Atlas

Evidence entries

713records·519peptides

Showing reference-linked Blood-brain barrier (BBB) evidence with reported value, assay context, interpretation role, and reference access kept separate.

Assay context

Evidence role

All713 Curated comparable0

#	Endpoint	Peptide		Assay context	Evidence role	Reference
1	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0002816	0.006 mL/g/min Unidirectional influx (Kin / PS product)	Intravenous injection (multiple time regression)blood-brain barrier	Comparable	Open
2	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0010467	42.5 % Brain uptake (%ID/g)	(Co)-cultureblood-brain barrier	Comparable	Open
3	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0012630	3.1 x 10^-7 cm/s Permeability coefficient (Papp/Pe)	(Co)-cultureblood-brain barrier	Comparable	Open
4	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0007295	71.26 % Brain uptake (%ID/g)	Capillary depletionblood-brain barrier	Comparable	Open
5	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0019431	0.008 mL/g/min Unidirectional influx (Kin / PS product)	In situ brain perfusionblood-brain barrier	Comparable	Open
6	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0023722	0.013 mL/g Brain–plasma partition (Kp)	Intravenous injection (multiple time regression)blood-brain barrier	Comparable	Open
7	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0029689	22 pg/mg brain tissue Brain concentration	Intracarotid injectionblood-brain barrier	Comparable	Open
8	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0022004	7.6 x 10^-6 cm/s Permeability coefficient (Papp/Pe)	PAMPAblood-brain barrier	Comparable	Open
9	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0032261	0.001 mL/g/min Unidirectional influx (Kin / PS product)	Intravenous injection (multiple time regression)blood-brain barrier	Comparable	Open
10	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0017661	1.85 x 10^-4 mL/g/min Unidirectional influx (Kin / PS product)	Intravenous injection (multiple time regression)blood-brain barrier	Comparable	Open
11	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0025642	5.2 x 10^-6 cm/s Permeability coefficient (Papp/Pe)	BMECblood-brain barrier	Comparable	Open
12	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0006936	3.86 x 10^-4 mL/g/min Unidirectional influx (Kin / PS product)	Intravenous injection (multiple time regression)blood-brain barrier	Comparable	Open
13	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0021924	0.001 mL/g Brain–plasma partition (Kp)	In situ brain perfusionblood-brain barrier	Comparable	Open
14	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0015863	1.5 x 10^-6 cm/s Permeability coefficient (Papp/Pe)	(Co)-cultureblood-brain barrier	Comparable	Open
15	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0028141	0.35 % injected dose/g brain Brain uptake (%ID/g)	Intracarotid injectionblood-brain barrier	Comparable	Open
16	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0023903	8 pmol/L Brain concentration	Intraperitoneal injectionblood-brain barrier	Comparable	Open
17	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0035775	0.019 mL/g Brain–plasma partition (Kp)	Intravenous injection (multiple time regression)blood-brain barrier	Comparable	Open
18	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0003230	0.002 mL/g Brain–plasma partition (Kp)	Capillary depletionblood-brain barrier	Comparable	Open
19	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0012433	0.046 %/g Brain uptake (%ID/g)	Intravenous injection (multiple time regression)blood-brain barrier	Comparable	Open
20	Blood-brain barrier (BBB) Distribution / Barrier	ATLPC0028642	5.3 x 10^-6 cm/s Permeability coefficient (Papp/Pe)	PAMPAblood-brain barrier	Comparable	Open

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Measurements

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Evidence entries